Abstract: Objective To explore the general rule and the characteristics of adverse drug reaction(ADR) induced by Shenmai injection and to provide some references for clinical medicine and rational use of drug. Methods One part of the ADR reports were collected by Zhongshan People's Hospital of 2008 to 2009, another part of the reports were collected by national journals of 1994 to 2009. 170 ADR则eports were analyzed using retrospective study method. Results ADR appeared mostly in the 40 age group, and more in female. The onset of ADR was usually within the first 30 min during the infusion. and the clinical manifestations of ADR were various, of which the allergic reaction was the most common. Conclusion Doctors and pharmacists should pay more attention to the ADR of Shenmai injection for the Immediate allergic reaction.

Key words: Shenmai injection, adverse drug reaction(ADR), analysis