One Case of Immune-Related Cystitis Caused by Sintilimab Injection

doi:10.19803/j.1672-8629.20250124

Abstract

Abstract: Objective To analyze one case of immune-related cystitis induced by immune checkpoint inhibitors (ICIs) and provide references for clinical medications. Methods One case of immune-related cystitis caused by sintilimab was discussed, and related literature was reviewed to summarize its clinical characteristics and treatments. Results The association between sintilimab and immune-related cystitis was close. After quick symptomatic treatment, the patient was discharged after the symptoms improved. Conclusion There are currently no definitive diagnostic criteria for immune-related cystitis, which is a rare immune-related adverse event (irAEs). Immune-related cystitis is likely if a patient has used ICIs, presents with urinary irritation symptoms, and shows no response to anti-infective treatment.

Key words: Sintilimab, ICIs, Immune-Related Cystitis, irAEs, Adverse Drug Reactions

CLC Number:

R979
R994.11

HUANG Huiling, TONG Fangqin, SONG Lu. One Case of Immune-Related Cystitis Caused by Sintilimab Injection[J]. Chinese Journal of Pharmacovigilance, 2025, 22(12): 1437-1440.

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https://zgywjj.magtechjournal.com/EN/Y2025/V22/I12/1437

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