Tissue Distribution of Chemical Components Based on Characters of Polygonum multiflorum Thunb.

doi:10.19803/j.1672-8629.20240808

Abstract

Abstract: Objective To analyze the differences in tissue accumulation of chemical components in Polygonum multiflorum Thunb. pieces with different characters and characteristics, and to reveal the differences and correlations between characters, chemical components and tissues. Methods The contents of stilbene glucoside, emodin, emodin -8-O-β-D- glucoside, emodin methyl ether and emodin methyl ether -8-O-β-D- glucoside in different tissues of Polygonum multiflorum Thunb were determined with UPLC-QQQ-MS/MS, and the distribution of chemical components in four tissues of Polygonum multiflorum Thunb. with different characteristics was compared while their correlations with different tissues were explored using such statistical methods as ANOVA and Pearson correlation analysis. Results Trans-2,3,5,4'-tetrahydroxydiphenyl ethyl-2-O-β-D- glucoside was obviously accumulated in the cork. The results of one-way ANOVA showed that there were significant differences in the tissue distribution of five main chemical components in Polygonum multiflorum Thunb. The results of correlation analysis showed that the contents of five chemical components in Polygonum multiflorum Thunb. from Gaozhou and Deqing,Guangdong and Qujing, Yunnan were significantly correlated with their parts (P<0.05). There was a positive correlation between the center of Polygonum multiflorum Thunb. from Qujing, Yunnan and emodin -8-O-β-D- glucoside from Yunjin (P <0.05). The cork of Polygonum multiflorum Thunb. from Gaozhou, Guangdong was negatively correlated with emodin -8-O-β-D- glucoside of abnormal vascular bundle (P<0.05), and the central vascular bundles of Polygonum multiflorum Thunb. was positively correlated with stilbene glucoside of abnormal vascular bundle of Polygonum multiflorum Thunb.( P <0.05).The results of one-way ANOVA showed that there were significant differences in the tissue distribution of five main chemical components in Polygonum multiflorum Thunb. The results of correlation analysis showed that the contents of five chemical components in Polygonum multiflorum Thunb. from Gaozhou and Deqing,Guangdong, Qujing Yunnan were significantly correlated with their parts (P<0.05). There was a positive correlation between the central vascular bundles of Polygonum multiflorum Thunb. from Qujing, Yunnan and emodin -8-O-β-D- glucoside from abnormal vascular bundle (P<0.05). The cork of Polygonum multiflorum Thunb. from Gaozhou, Guangdong was negatively correlated with emodin -8-O-β-D- glucoside of Yunjin (P <0.05), and the central vascular bundles of Polygonum multiflorum Thunb. was positively correlated with stilbene glucoside of abnormal vascular bundle(P<0.05). Conclusion The distribution of chemical components in Polygonum multiflorum Thunb. tissues with different characters and characteristics has been characterized, which provides data for quality evaluation of Polygonum multiflorum Thunb.

Key words: Polygonum multiflorum Thunb., Character, Stilbene Glycosides, Anthraquinone, Distribution, Correlation

CLC Number:

R917

WANG Qi, YANG Yanrong, LI Yanyi, XIE Jingxin, WEI Feng, MA Shuangcheng, WANG Fang, SHI Jia. Tissue Distribution of Chemical Components Based on Characters of Polygonum multiflorum Thunb.[J]. Chinese Journal of Pharmacovigilance, 2024, 21(12): 1371-1376.

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https://zgywjj.magtechjournal.com/EN/Y2024/V21/I12/1371

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