Chinese Journal of Pharmacovigilance ›› 2025, Vol. 22 ›› Issue (3): 343-345.
DOI: 10.19803/j.1672-8629.20240464

• Orginal Article • Previous Articles     Next Articles

One Case of Acute Hepatic Injury Caused by Ioversol Injection

YU Li, TAN Xiying*   

  1. Department of Pharmacy, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing Jiangsu 210029, China
  • Received:2024-07-04 Online:2025-03-15 Published:2025-03-17

Abstract: Objective To analyze one case of hepatic injury caused by ioversol injection in order to provide a reference for clinical use. Methods The clinical data of a 70-year-old male patient who experienced persistent elevation of liver enzymes after receiving ioversol injection was analyzed. The correlations between hepatic injury and ioversol injection were studied, and a literature review was conducted to identify cases of contrast agent-induced hepatic injury and potential causes. Results Based on correlation assessment, the severe liver injury in this patient was believed to have been caused by administration of ioversol injection. The patient’s liver function gradually improved after hepatoprotective treatment. Conclusion Ioversol injection may cause adverse reactions that lead to hepatic dysfunction. Clinicians should be aware of the risk of adverse drug reactions associated with ioversol injection and enhance monitoring.

Key words: Ioversol, Injection, Contrast, Acute Hepatic Injury, Liver Enzymes, Adverse Drug Reaction

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