One Case of Acute Drug-Induced Liver Injury Caused by Tingli Jiangxuezhi Capsules

doi:10.19803/j.1672-8629.20240453

Abstract

Abstract: Objective To identify the components of Tingli Jiangxuezhi capsules that may cause liver injury so as to provide a reference for safe and rational drug use. Methods One case of liver injury caused by Tingli Jiangxuezhi capsules was analyzed and the correlation between liver injury and components of this drug was studied based on related reports from CNKI, Wanfang, and VIP database that were published from inception to June 20, 2024. Results Before admission to the hospital, the patient was treated with Tingli Jiangxuezhi capsules alone, so these capsules were considered to have caused acute drug-induced liver injury after admission despite the lack of related literature. Rhei radix et rhizome, Scutellariae radix and Aucklandiae radix contained in these capsules could all cause liver injury. Conclusion Rhei radix et rhizome, Scutellariae radix and Aucklandiae radix may lead to liver injury, so clinicians and pharmacists should be alert to the occurrence of such adverse reactions.

Key words: Tingli Jiangxuezhi, Capsules, Drug-induced Liver Injury, Rhei radix et rhizoma, Scutellariae radix, Aucklandiae radix, Adverse Drug Reaction

CLC Number:

HU Yaping, ZHANG Aiwu. One Case of Acute Drug-Induced Liver Injury Caused by Tingli Jiangxuezhi Capsules[J]. Chinese Journal of Pharmacovigilance, 2025, 22(2): 224-226.

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URL: https://zgywjj.magtechjournal.com/EN/10.19803/j.1672-8629.20240453

https://zgywjj.magtechjournal.com/EN/Y2025/V22/I2/224

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