Quality evaluation of adverse drug reaction reports in oncology department based on weighted Topsis-rank-sum ratio method

doi:10.19803/j.1672-8629.20220026

Abstract

Abstract: Objective To establish a comprehensive system for evaluating the quality of adverse drug reaction (ADR) reports and provide reference for objective evaluation of quality of ADR reports in an oncology department. Methods Quality evaluation standards for ADR reports were established according to the related scoring standards and documents. A combination of weighted Topsis and rank sum ratio (RSR) was used to evaluate and classify the quality of 120 original ADR reports submitted to the Department of Pharmacy by the Department of Oncology at Bozhou People’s Hospital in 2021. Results Twenty reports were of medium quality (C_i＞0.570 0), 75 reports were up to the standard (0.360 0＜C_i≤0.570 0) and 25 reports fell short of the standard (C_i≤0.360 0). The main problems included inadequate descriptions of processes of ADRs, incorrect or incomplete drug information. Conclusion Quality evaluation of ADR reports based on the weighted Topsis–RSR method can help avoid the limitations of a single approach. This method is feasible and effective. The results of evaluation suggest that the quality of ADR reports by the Department of Oncology at our hospital needs to be improved.

Key words: adverse drug reaction, report quality, weighted Topsis method, rank-sum ratio, oncology

CLC Number:

WU Na, SU Dan, WANG Haikun, SHEN Aizong. Quality evaluation of adverse drug reaction reports in oncology department based on weighted Topsis-rank-sum ratio method[J]. Chinese Journal of Pharmacovigilance, 2023, 20(1): 101-105.

References

[1] National Medical Products Administration. National Adverse drug reaction monitoring report (2021)[EB/OL].(2022-03-30)[2022-04-21]. https://www.nmpa.gov.cn/xxgk/yjjsh/ypblfytb/20220329161925106.html.
[2] CAO X, SUN YQ, HUANG GM, et al.Signal mining and analysis of adverse reactions induced by tacrolimus and voriconazole[J]. Chinese Journal of Pharmacovigilance(中国药物警戒), 2021, 18(5): 483-488.
[3] WEI YY, LI F, TAO XM, et al.Prevention of adverse reactions of antibiotics in a respiratory department[J]. Chinese Journal of Pharmacovigilance(中国药物警戒), 2021, 18(11): 1083-1086.
[4] SUN B, LIU X, ZHANG EF, et al.Evaluation of drug use evaluation of imipenem and cilastatin based on weighted TOPSIS method[J]. Chinese Journal of Pharmacoepidemiology(药物流行病学杂志), 2021, 30(12): 827-832.
[5] GU SY, LIANG YY, ZHANG KY, et al.Fuzzy combination of TOPSIS and RSR for comprehensively assessing the quality of national essential public health services[J]. Chinese General Practice(中国全科医学), 2022, 25(4): 432-437.
[6] YANG FN, LI Y.Application of TOPSIS method combined with rank sum ratio method in work quality evaluation of maternal health care[J]. Chinese Nursing Research(护理研究), 2021, 35(18): 3231-3234.
[7] SONG L, TIAN WJ, JI HH, et al.Drug use evaluation of vancomycin used in neonates based on weighted TOPSIS method[J]. Chinese Journal of New Drugs and Clinical Remedies(中国新药与临床杂志), 2016, 35(5): 369-373.
[8] WANG Y.Applications of TOPSIS weighted and RSR in the influences comprehensive evaluation of academic journals[J]. Library And Information Service(图书情报工作), 2013, 57(2): 92-96.
[9] National Center for Adverse Drug Reaction Monitoring. Notice on issuing guidelines on Quality Assessment of ADR Case Reports(Trial)[S]. Beijing: National Center for Adverse Drug Reaction Monitoring, 2009: 4.
[10] National Medical Products Administration. Measures for the administration of ADR reporting and monitoring(Decree no. 81 of the Ministry of Health)[EB/OL].(2011-07-01)[2022-01-29]. https://www.nmpa.gov.cn/xxgk/fgwj/bmgzh/20110504162501325.html.
[11] National Center for Adverse Drug Reaction Monitoring. WHO Glossary of Adverse Drug Reactions(WHO药品不良反应术语集)[M]. Beijing: China Medical And Technology Press, 2003.
[12] LIU JB, QU CY, WANG RH.Comprehensive evaluation of Topsis based on attribute AHM and its application[J]. Modern Preventive Medicine(现代预防医学), 2006, 33(10): 1862-1863.
[13] FAN GS, WEI L, LI YJ, et al.Realization of TOPSIS method in WPS table[J]. Information Technology & Informatization(信息技术与信息化), 2020(6): 59-63.
[14] TIAN FD.Grading problem in RSR method[J]. Chinese Journal of Health Statistics(中国卫生统计), 1993, 10(2): 26-28.
[15] CHEN LH, AN LY, SHI P, et al.Methods for quality evaluation of individual case reports of adverse drug reactions in China[J]. Chinese Journal of Pharmacovigilance(中国药物警戒), 2020, 17(3): 148-153.
[16] SHEN AZ, NV TT, JIANG L, et al.Study on quality evaluation index system of ADR/ADE reporting[J]. Chinese Journal of Hospital Pharmacy(中国医院药学杂志), 2013, 33(23): 1977-1981.
[17] NIU R, XIANG YF, ZHANG Z, et al.Establishment of quality assessment system for adverse drug reaction reports[J]. Herald of Medicine(医药导报), 2019, 38(6): 815-819.
[18] LIU GM, WANG QJ.Comprehensive evaluation on the quality of child health care service in China in 2017 with TOPSIS and RSR methods[J]. Modern Preventive Medicine(现代预防医学), 2020, 47(4): 644-647.