Chinese Journal of Pharmacovigilance ›› 2022, Vol. 19 ›› Issue (7): 712-716.
DOI: 10.19803/j.1672-8629.2022.07.04
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ZHANG Dousheng, WANG Chen#, XU Mingzhe*
Received:
2022-02-15
Online:
2022-07-15
Published:
2022-07-12
CLC Number:
ZHANG Dousheng, WANG Chen, XU Mingzhe. Rapid evaluation of potential neurotoxicity of levornidazole for injection and its main impurities based on computational models and database technology[J]. Chinese Journal of Pharmacovigilance, 2022, 19(7): 712-716.
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[1] ZHANG Q, YAN JZ, YAO W, et al.Study on the legal system of drug reevaluation in america, european union, Japan and the Enlightenment to China[J]. China Pharmacy(中国药房), 2019, 30(18): 2449-2454. [2] ZHANG YP, SONG SY, BAO LL.Relationship between mechanism and chemical structure of adverse reactions of fluoroquinolones[J]. China & Foreign Medical Treatment(中外医疗), 2014, 33(7): 130-131. [3] GE YQ, YE XX, LE J, et al.Research progress on toxicity and detection methods of N-nitrosamines genotoxic impurities[J]. Chinese Journal of Pharmaceutical Analysis(药物分析杂志), 2020, 40(1): 83-89. [4] ADAMSON RH, CHABNER BA.The finding of N-nitrosod-imethylamine in common medicines[J]. The Oncologist, 2020, 25(6): 460-462. [5] MICHAEL WC.Understanding and preventing (N-nitrosod-imethylamine) NDMA contamination of medications[J]. The Annals of Pharmacotherapy, 2020, 54(6): 611-614. [6] HU JL, WU T, ZHU DM, et al.In vitro activity of a new antibac-terial agent levornidazole against anaerobic bacteria[J]. Chinese Journal of Infection and Chemotherapy(中国感染与化疗杂志), 2014, 14(2): 18-21. [7] LI WW, YAO MN, ZHAO X, et al.Systematic evaluation of levornidazole in the treatment of anaerobic infection[J]. Chinese Journal of Pharmacoepidemiology(药物流行病学杂志), 2019, 28(3): 13-19. [8] HU J, ZHANG J, CHEN Y, et al.In vitro anaerobic pharma-cokinetic/ pharmacodynamic model to simulate the bactericidal activity of levornidazole against bacteroides fragilis[J]. Clinical Therapeutics, 2017, 39(4): 828-836. [9] ZHAO Y, CHEN Z, HUANG P, et al.Analysis of ornidazole injection in clinical use at post-marketing stage by centralized hospital monitoring system[J]. Current Medical Science, 2019, 39(5): 836-842. [10] SUN JH, WANG ZQ, GU XL, et al.Comparative study of ornidazole enantiomers on the toxic and side effects to central nervous system in mice[J]. Journal of China Pharmaceutical University(中国药科大学学报), 2008, 39(4): 343-347. [11] BAI YT, NAN N, YIN J.Discussion on toxicity prediction of quantitative structure-activity relationship model and its application in impurity prediction[J]. Chinese Pharmaceutical Affairs(中国药事), 2019, 33(10): 1174-1180. [12] LI L, YANG JB.Application progress of physiologically-based pharmacokinetic model in clinicaldevelopment of novel molecular entities[J]. Chinese Journal of Clinical Pharmacology(中国临床药理学杂志), 2017, 33(17): 118-122. [13] PURI M, PATHAK YV, SUTATIYA VK, et al Artificial neural network for drug design, delivery and disposition[M]. Academic press: Salt lake city, USA, 2016: 181-193. [14] SAMUI P, ROY SS, VALENTINA EB.Handbook of neural computation[M]. Academic press: Salt Lake City, USA, 2017: 515-535. [15] GAO YF, FENG JF, ZHU L.Toxicodynamic modeling of zebrafish larvae to metals using stochastic death and individual tolerance models: comparisons of model assumptions, parameter sensitivity and predictive performance[J]. Ecotoxicology, 2017, 26(3): 295-307. [16] AUSTIN JD, HIRSTEIN J, WALEN S.Integrated mathematics interfaced with science[J]. School Science and Mathematics, 1997, 97(1): 45-49. [17] PABLO MC, PARDO-FERNÁNDEZ JC. The youden index in the generalized receiver operating characteristic curve context[J]. The International Journal of Biostatistics, 2019, 15(1): 1-20. [18] JOHN AC.Classical and modern regression with applications[J]. Technometrics, 2012, 29(3): 377-378. [19] KUHN M, LETUNIC I, JENSEN LJ, et al.The SIDER database of drugs and side effects[J]. Nucleic Acids Research, 2016, 44(D1): D1075-D1079. [20] LEI TL, LI YY, SONG YL, et al.ADMET evaluation in drug discovery: 15 accurate prediction of rat oral acute toxicity using relevance vector machine and consensus modeling[J]. Journal of Cheminformatics, 2016, 8(1): 1-19. |
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