Analysis of one case of hemorrhagic goiter caused by aspirin tablets in one patient with coronary heart disease

doi:10.19803/j.1672-8629.20211205

Abstract

Abstract: Objective To study the effect of aspirin on the thyroid gland. Methods By analyzing one case of hemorrhagic goiter caused by aspirin, the correlations between medication and adverse drug reactions were investigated. Results Before the patient took aspirin, ultrasound of the patient’s thyroid gland showed multiple nodules and normal thyroid function. Twenty-four days after taking the medicine, the patient’s neck became increasingly swollen, and the thyroid ultrasound showed blood flow signals. After four months, she came back to see a doctor and a pharmacist, both of whom suggested discontinuing aspirin and rechecking thyroid function. Ten days after drug withdrawal, the swelling of the neck gradually shrank. More than one month later, the swelling completely subsided. No blood flow signal was found by thyroid ultrasound. Conclusion Goiter among patients taking aspirin may be caused by aspirin-related bleeding, which should attract the attention of doctors and pharmacists. It is suggested that patients taking aspirin should have their thyroid function examined and receive thyroid ultrasound examination in case of goiter, especially those with previous thyroid diseases.

Key words: thyroid, coronary heart disease, aspirin, bleeding, adverse drug reaction, pharmaceutical analysis

CLC Number:

R972
R994.11

DING Qian, LI Boyu, ZHANG Qingxia. Analysis of one case of hemorrhagic goiter caused by aspirin tablets in one patient with coronary heart disease[J]. Chinese Journal of Pharmacovigilance, 2023, 20(2): 209-212.

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