Abstract: Objective To identify the components of Shangfengting capsules that may cause liver injury so as to provide reference for clinical rational drug use. Methods One case of liver injury caused by Shangfengting capsules was reported and the correlation between liver injury and the main components of this drug was analyzed. CNKI, Wanfang and VIP databases were searched for related literature that was published between inception and July 19, 2021. Results There were no related reports about liver injury caused by Tantanting capsules, but the ephedra in the formula could cause hepatocellular liver injury, and the mechanism was not clear. Conclusion Ephedra may lead to liver injury, so clinicians and pharmacists should manage to ensure the rational use of drugs to reduce and prevent liver injury.

Key words: Shangfengting capsules, drug induced liver injury, ephedra, adverse drug reaction