Pharmaceutical Care of a Patient Suspected to Be Allergic to Meropenem and Treated with Imipenem/Cisstatine Sodium

doi:10.19803/j.1672-8629.2021.09.20

Abstract

Abstract: Objective To investigate the pharmaceutical care of one patient allergic to carbapenems and analyze the occurrence and mechanism of cross-reactivity betweenβ-lactams and carbapenems. Methods The medication of an elderly male patient who had been treated with meropenem following severe abdominal infection after colon cancer surgery and developed skin rash was analyzed. The patient was then treated with imipenem acetaminophen sodium in conjunction with anti-allergy drugs and pharmaceutical care. Results After twenty days of anti-infection treatment, the patient’s rash subsided and there were no other allergic reactions before he was discharged after improvement. Conclusion Limited studies have shown that the occurrence of allergies is mainly related to the side chain. If carbapenem has to be used, cautious administration of an alternative carbapenem should be considered for patients with previous allergy to another carbapenem.

Key words: meropenem, imipenem/cisstatine, allergy

CLC Number:

R969.3

MA Xue, QI Tingting, YU Wentao. Pharmaceutical Care of a Patient Suspected to Be Allergic to Meropenem and Treated with Imipenem/Cisstatine Sodium[J]. Chinese Journal of Pharmacovigilance, 2021, 18(9): 887-889.

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