One case of Hypersensitivity Syndrome Induced by Oxcarbazepine Combined with Olanzapine and Piropilone

doi:10.19803/j.1672-8629.2021.01.17

Abstract

Abstract: Objective To analyze the drug-induced hypersensitivity syndrome (DISH) caused by the combination of oxcarbazepine,olanzapine and piropilon.Methods The clinical data about one patient with schizophrenia who developed fever,redness of the skin with rash and abnormalities of the blood system caused by olanzapine,oxcarbine and piropilon was analyzed based on related literature at home and abroad.Results and Conclusion Oxcarbazepine is probably an allergenic drug that causes DISH.However,genetic testing before drug administration is still not easily accessible,so early identification of DISH and quick drug discontinuation are the keys to reducing severe adverse reactions.

Key words: oxcarbazepine, olanzapine, piropilone, drug induced hypersensitivity syndrome

CLC Number:

R994.11

LI Huanfen, WANG Jinbao, WANG Laihai, ZHANG Ruiling. One case of Hypersensitivity Syndrome Induced by Oxcarbazepine Combined with Olanzapine and Piropilone[J]. Chinese Journal of Pharmacovigilance, 2021, 18(1): 84-86.

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