Antibiotic Application of Myasthenia Gravis Complicated with Infection

doi:10.19803/j.1672-8629.2019.10.11

Abstract

Abstract: Myasthenia gravis( MG ) is an acquired autoimmune disease that primarily affects the postsynaptic membrane acetylcholine receptors of neuromuscular junctions. Infection is one of the most common complications in the development of MG. However, some antibacterial drugs interfere with the movement of nerve-muscle joints, which may aggravate the symptoms of MG and even induce myasthenic crisis. Therefore, cautious selection of antibacterial drugs is particularly important for MG patients. This paper summarizes the antibacterial drugs that affect the symptoms of MG, and raise recommendations for the selection of antibacterial drugs in order to provide reference for clinicians to use antibacterial drugs and for new drug research and development.

Key words: myasthenia gravis, infection, neuromuscular block, antibiotics

CLC Number:

R978.1

PAN Weirong, SHEN Xian, SUN Sixian, ZHU Xuying. Antibiotic Application of Myasthenia Gravis Complicated with Infection[J]. Chinese Journal of Pharmacovigilance, 2019, 16(10): 625-631.

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