One case of neuromuscular block caused by clindamycin phosphate for injection

doi:10.19803/j.1672-8629.20240295

Abstract

Abstract: Objective To investigate such adverse reactions as neuromuscular blockade caused by clindamycin phosphate for injection so as to provide references for clinical safe use. Methods Based on related literature, one case of myasthenia gravis in a 51-year-old patient with periodontal abscess after receiving clindamycin phosphate for injection was analyzed. Results The patient experienced muscle weakness after taking tinidazole and clindamycin phosphate for injection. The symptoms were considered to be adverse reactions related to clindamycin phosphate for injection. After symptomatic treatment, the patient's muscle strength was largely normalized. Conclusion In case of myasthenia gravis, the possibility of the symptoms being caused by clindamycin phosphate for injection should be considered. Clindamycin phosphate for injection should be used with caution in patients who are taking neuromuscular blocking drugs concurrently.

Key words: clindamycin, injection, neuromuscular blockade, muscle weakness, adverse drug reactions

CLC Number:

R978
R994.11

ZHANG Hao, CAO Shugang, HE Jun, XU Wenan, XIA Mingwu. One case of neuromuscular block caused by clindamycin phosphate for injection[J]. Chinese Journal of Pharmacovigilance, 2024, 21(10): 1178-1180.

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https://zgywjj.magtechjournal.com/EN/Y2024/V21/I10/1178

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