心可舒临床研究进展

doi:10.19803/j.1672-8629.20240997

摘要/Abstract

摘要： 目的探讨心可舒在心血管疾病治疗中的多靶点、多途径作用,为后续研发新型心血管药物和深入研究其临床效果提供参考。方法通过查阅近5年相关文献,总结心可舒的药理作用、作用机制及临床应用研究进展,分析其在改善心功能、缓解焦虑、抑郁症状等效果及安全性。结果研究表明心可舒具有多靶点、多途径的药理作用,能够显著改善患者心功能,缓解心悸、胸闷、心绞痛等症状;同时对焦虑、抑郁症状也有一定的改善效果。心可舒安全性较高,未发现明显不良反应。结论心可舒作为一种具有活血化瘀、行气止痛功效的中成药,在治疗气滞血瘀引起的心悸、胸闷、冠心病心绞痛、高血压、高血脂和心律失常等方面表现出良好的疗效和安全性。

关键词: 心可舒, 药理作用, 药理机制, 心血管疾病, 双心病, 临床应用

Abstract: Objective To explore the multi-target and multi-channel effects of Xinkeshu in the treatment of cardiovascular diseases in order to provide a reference for subsequent development of new cardiovascular drugs. Methods Based on related literature published over the past five years, the pharmacological effects, mechanism of action and clinical applications of Xinkeshu were summarized. The role of Xinkeshu in improving cardiac function and relieving anxiety/ depression was analyzed before its safety was evaluated. Results Studies showed that Xinkeshu had multi-target and multi-channel pharmacological effects. This drug could significantly improve the cardiac function of patients, relieve palpitations, chest tightness and angina pectoris while mitigating anxiety/depression. It was highly safe in that no obvious adverse reactions were found. Conclusion As a Chinese patent medicine that can help promote blood circulation, remove blood stasis, strengthen qi and relieve pain, Xinkeshu is effective and safe in treating palpitation, chest tightness, angina pectoris, hypertension, hyperlipidemia and arrhythmia caused by qi stagnation and blood stasis.

Key words: Xinkeshu, Pharmacological Action, Pharmacological Mechanism, Cardiovascular Disease, Double Heart Disease, Clinical Application

中图分类号:

马玉琴, 刘祥欢, 张硕, 徐艺珈, 赵明沂. 心可舒临床研究进展[J]. 中国药物警戒, 2025, 22(11): 1310-1314.

MA Yuqin, LIU Xianghuan, ZHANG Shuo, XU Yijia, ZHAO Mingyi. Research Progress in Efficacy of Xinkeshu[J]. Chinese Journal of Pharmacovigilance, 2025, 22(11): 1310-1314.

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https://zgywjj.magtechjournal.com/CN/Y2025/V22/I11/1310

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