中国药物警戒 ›› 2012, Vol. 9 ›› Issue (11): 693-695.

• 药械安全性研究 • 上一篇    下一篇

56例参麦注射液不良反应分析

周晶鑫   

  1. 哈尔滨市药品不良反应监测中心,黑龙江 哈尔滨 150016
  • 收稿日期:2012-03-21 出版日期:2012-11-10 发布日期:2015-08-07
  • 作者简介:周晶鑫,女,主管药师,药械不良反应/事件监测。

Analysis of 56 Cases of Adverse Drug Reaction Induced by Shenmai Injection

ZHOU Jing-xin   

  1. Harbin Center for ADR Monitoring, Heilongjiang Harbin 150016, China
  • Received:2012-03-21 Online:2012-11-10 Published:2015-08-07

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摘要： 目的了解参麦注射液不良反应发生的一般规律,促进临床合理用药。方法对哈尔滨市2010年1月~2012年6月有关参麦注射液的56例不良反应报告从患者基本情况、不良反应发生时间、临床表现、用药情况等方面进行统计分析。结果用药患者以中老年人居多,平均年龄53.28岁;在30min内发生ADR的占总例数的83.93%;累及皮肤及其附件的报告最多,为28例,占36.36%;均为单独用药后发生的ADR的报告。结论参麦注射液ADR的发生与药物因素有关,并且年龄分布特点符合该药的适用人群。临床医师、药师应重视参麦注射液的不良反应,加强其应用过程中的监测,合理用药。

关键词: 参麦注射液, 药品不良反应, 中药注射剂

Abstract: Objective To analyze the characteristics of ADR induced by Shenmai injection so as to promote the rational use of the drugs． Methods 56 cases of ADR relate to the Shenmai injection from January 2010 to June 2012 in Harbin were analyzed statistically from patients with normal circumstances, adverse reaction time, clinical manifestation, drug use and other aspects. Results Most of the patients taking the drug were old people whose average age was 53.28. The cases occurred within 30 minutes account for 83.93 % of the total. Most of the reports(n=28) involved both of the skin system and its appendages, accounting for 36.36%. All of these cases were single medication using. Conclusion The ADR of Shenmai injection was related to the pharmaceutical factors. What's more, age distribution accorded with the indications for the crowd of the drug. Enterprises, doctors and pharmacists should pay more attention to the ADR of Shenmai injection. The process of drug use should be monitored to reduce the incidence of ADR.

Key words: Shenmai injection, adverse drug reactions