基于产地和炮制工艺探讨何首乌化学成分变化

doi:10.19803/j.1672-8629.2022.07.24

中国药物警戒 ›› 2022, Vol. 19 ›› Issue (7): 799-802.
DOI: 10.19803/j.1672-8629.2022.07.24

基于产地和炮制工艺探讨何首乌化学成分变化

李妍怡¹, 张玉杰¹, 汪祺^2#, 马双成^2,*

¹北京中医药大学中药学院,北京 102400;
²中国食品药品检定研究院,北京 100050

收稿日期:2021-04-19 出版日期:2022-07-15 发布日期:2022-07-12
通讯作者: ^*马双成,男,博士,研究员,中药民族药质量标准及安全性评价研究。E-mail：masc@nifdc.org.cn;^#为共同通信作者。
作者简介:李妍怡,女,在读博士,中药分析。
基金资助:
国家自然科学基金资助项目（81503347,81973476)

Chemical constituents of Polygonum multiflorum Thunb. based on its origins and methods of processing

LI Yanyi¹, ZHANG Yujie¹, WANG Qi^2#, MA Shuangcheng^2,*

¹School of Chinese Materia medica, Beijing University of Chinese Medicine, Beijing 102400, China;
²National Institutes for Food and Drug Control, Beijing 100050, China

Received:2021-04-19 Online:2022-07-15 Published:2022-07-12

摘要/Abstract

摘要： 何首乌作为典型的生熟异治类中药,其药效物质是目前研究热点之一。本文总结近10年文献,发现3年生的何首乌于10月至12月采收最佳,并针对目前常见的几种炮制方法进行化学成分（蒽醌类、二苯乙烯苷类、黄酮类等）变化规律探讨,以期为何首乌质量标准的建立及其毒效物质基础的深入研究提供参考。

关键词: 何首乌, 二苯乙烯苷, 蒽醌, 基原, 炮制, 毒性

Abstract: Polygonum multiflorum Thunb. is a typical traditional Chinese medicine, the medicinal effect and material basis of which are one of the current research hotspots. This article summarizes the related literature that has been published over the past ten years. It is found that three-year-old P. multiflorum is best harvested between October and December. The ways in which its chemical components vary are also studied. It is hoped that this research can contribute to the establishment of quality standards and the in-depth study of its toxic substances.

Key words: Polygonum multiflorum Thunb., stilbene glycoside, anthraquinone, botanic origin, processing, toxicity

中图分类号:

R969

李妍怡, 张玉杰, 汪祺, 马双成. 基于产地和炮制工艺探讨何首乌化学成分变化[J]. 中国药物警戒, 2022, 19(7): 799-802.

LI Yanyi, ZHANG Yujie, WANG Qi, MA Shuangcheng. Chemical constituents of Polygonum multiflorum Thunb. based on its origins and methods of processing[J]. Chinese Journal of Pharmacovigilance, 2022, 19(7): 799-802.

参考文献

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基于产地和炮制工艺探讨何首乌化学成分变化

Chemical constituents of Polygonum multiflorum Thunb. based on its origins and methods of processing

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