Abstract: ObjectiveThe reporting data of adverse drug reaction has been increasing more and more rapidly. Whereas, the existing nonstandard data decreased the efficiency of adverse drug reaction monitoring and evaluation, and influenced the effective use of the data. By discussing the methods and applications of data normalization, to provide reference and suggestion for improving the quality of reports. MethodsOn the basis of our real working practices in data normalization, the case reports from the monitoring system were studied, non standard reports were summarized and the reasons were analyzed, the methods of data normalization and reporting quality improvement were discussed. ResultsThe standard databases and the rule databases were created, they were capable of automatic completion of the standardization work of the new cases. ConclusionThe data normalization is an effective method for improving the quality of the reports, it plays an important role in the actual work. Improving the quality of the reports is a systematic project , it needs the joint efforts of all the parties.

Key words: adverse drug reaction, data normalization, monitoring system