Abstract: ObjectiveTo introduce the ADR rapid reporting and intelligent searching system which is based on HIS system with a purpose of setting up a information technology support platform for carrying out active monitoring of drug safety and evaluation, and improving traditional methods of drug safety monitoring and evaluation. MethodsThe ADR rapid reporting and intelligent searching system was established through the literature research and on the basis of in-depth business analysis and technology research, adopting J2EE, Enterprise Java Bean and other JAVA-based technology. And the system was carried on practical application in multiple medical institutions of Guangdong, Guizhou and other places for the purpose of testing and improving. ResultsThe development of ADR rapid reporting and intelligent searching system based on HIS significantly solved under reporting, misinformation, delay reporting and other issues of adverse drug reactions, achieved rapid reporting and intelligent searching functions, improved the hospital's ADR reporting rate and the reporter's initiative, and let the adverse drug reaction monitoring mode turn from the traditional "passive" to the "active". ConclusionThe ADR rapid reporting and intelligent searching system effectively enhances the capacity of drug post-marketing surveillance, and greatly improves the rational drug use in medical institutions, and it is of significant importance to strengthen drug safety monitoring and evaluation in our country.

Key words: adverse drug reaction, hospital information system, intelligent searching