Abstract: Objective To study the pharmacological effects of Lithospermum erythrorhizon on scalded rats in order to clarify its topical treatment function of burns. Methods 60 rats were randomly divided into 5 groups． We used the constant temperature water bath to manufacture rat burn model and measured the rat paw circumference with a soft tape measure. Foot swelling rate was evaluated with computer. Results Compared with the control group, there were significant differences in Lithospermum erythrorhizon high, low concentration group (P<0.05). Conclusion Homemade extract of Lithospermum erythrorhizon could treat hot water scaldand be suitable for clinical application.

Key words: Lithospermum erythrorhizon, extract, external use, scald