Preparation and quality evaluation of standard decoctions of Rosa chinensis Jacq.

doi:10.19803/j.1672-8629.20220717

Abstract

Abstract: Objective To establish a quality evaluation method for the standard decoctions of Rosa chinensis Jacq. so as to provide reference for the use and quality control of the standard decoction of Rosa chinensis Jacq..Methods Fifteen batches of prepared slices of Rosa chinensis Jacq. were collected from different areas of production to prepare standard decoctions. Hypericin and isoquercitrin were selected as indicators of quantitative detection to calculate the transfer rate while HPLC characteristic chromatograms were established and analyzed with the Similarity Evaluation System for Chromatographic Finger-print of Traditional Chinese Medicine (2012). Results Among the standard decoctions made from 15 batches of Rosa chinensis Jacq. samples, the extraction rate of the standard decoction of samples was 16.32%-23.22%. The transfer rates of hypericin and isoquercitrin ranged from 27.57% to 45.42% and from 34.38% to 49.71% respectively. Eleven common peaks were determined with four characteristic peaks identified．Moreover, the similarity was over 0.90. Conclusion A simple, stable and feasible method for the preparation and quality evaluation of standard decoctions of the Rosa chinensis Jacq. is established, which can provide reference for related research.

Key words: Rosa chinensis Jacq. pieces, standard decoction, hypericin, isoquercitrin, preparation process, quality standard, extraction rate, transfer rate, characteristic chromatogram

CLC Number:

R944.1

LI Ning, JIANG Xiaoya, ZHANG Zezhao, GAO Le, WANG Xinguo, LIU Xiaoming. Preparation and quality evaluation of standard decoctions of Rosa chinensis Jacq.[J]. Chinese Journal of Pharmacovigilance, 2023, 20(4): 397-402.

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