Abstract: Objective To observe the antivirus effects of Junduqing granule in vitro. Methods The cytopathic effect (CPE) method was adopted to study the inhibitory effect of Junduqing granule on respiratory syncytial virus (RSV), adenovirus (AdV) and coxsackie virus (CoxV) in vitro. The quantitative real-time PCR method was used to observe the inhibiting effect of Junduqing granule on EB virus BcLF and BARF1 genetic expression. Results Junduqing granule showed obvious inhibiting effect on the CPE induced by RSV, AdV and CoxV. And it also has obvious inhibiting effect on EB virus BcLF and BARF1 genetic expression. Conclusion Junduqing granule can inhibit respiratory virus, enterovirus and EB virus in vitro.

Key words: Junduqing granule, respiratory syncytial virus, adenovirus, coxsackie virus, epstein-barr virus