Chinese Journal of Pharmacovigilance ›› 2012, Vol. 9 ›› Issue (2): 104-109.

• Orginal Article • Previous Articles     Next Articles

Causation and Treatment Of Orthopedic Implants Adverse Events Systematic Review

TAO Qing-mei1, SUN Feng2, YU Kai3, ZHAI Wei4, ZHAN Si-yan1, *   

  1. 1 Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China;
    2 School of Pharmacy, Peking University, Beijing 100191, China;
    3 Tianjin Fifth Central Hospital; Tianjin 300450, China; Beijing Center for ADR Monitoring, Beijing 100024, China
  • Received:2011-06-23 Online:2012-02-10 Published:2015-08-10

Abstract: Objective To study the causation and treatment of orthopedic implants adverse events in China. MethodsArticles about orthopedic implants adverse events published by Nov. 2010 in China were searched. The causes and treatment of the adverse events were analyzed. ResultsAccording to our searching strategy and including criteria, 45 studies were included. The overall adverse events were caused by medical techniques, patient factors, medical implants and the comprehensive factors, the medical techniques covered 46.8%, was the main cause, and the comprehensive factors covered 31.8% among these four factors, different kinds of orthopedic implants showed the same way. The main treatment was operation which may be suitable to different cases. ConclusionThe main causes of orthopedic implants adverse events in China were medical techniques and the comprehensive factors, operation was most likely to apply when the adverse events happened, relative measures to control the main causes and researches to make sure the causes of the adverse events are needed to reduce the orthopedic implants adverse events incidence.

Key words: orthopedic implants, adverse events, causation, treatment, systematic review