Chinese Journal of Pharmacovigilance ›› 2025, Vol. 22 ›› Issue (5): 583-585.
DOI: 10.19803/j.1672-8629.20240804

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One Case of Taste Disorders Caused by Cetylpridinium Chloride Gargle

QIAN Xia1, ZHENG Liguang1,*, LI Tongtong2, HE Yachun3   

  1. 1Department of Pharmacy, Peking University School and Hospital of Stomatology, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing 100081, China;
    2Department of Resuscitation, Peking University School and Hospital of School, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing 100081, China;
    3Department of Implantation, Peking University School and Hospital of School, National Center of Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing 100081, China
  • Received:2024-10-08 Online:2025-05-15 Published:2025-05-19

Abstract: Objective To explore the therapeutic effect of cetylpirdinium chloride gargle while avoiding taste abnormalities and adverse reactions. Methods One case of taste disorder caused by cetylpirdinium chloride gargle was discussed. Based on a review of related reports at home and abroad, the cause of taste disorder and possible mechanisms were studied. Results Taste abnormalities caused by the use of cetylpirdinium chloride gargle were quite common globally. Early detection and interventions had to be carried out to restore taste. Conclusion The incidence of taste abnormalities caused by the use of cetylpirdinium chloride gargle remains relatively high. It is recommended that doctors and patients alike be aware of the likelihood of this adverse reaction. Once taste disorders occur, the drug should be discontinued quickly and symptomatic treatment initiated.

Key words: Cetylpirdinium, Chloride Gargle, Taste Disorder, Dysgeusia, Adverse Drug Reaction

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