Research Progress on Toxic Material Basis and Hepatotoxicity Mechanism of Polygonum Multiflorum

Abstract

Abstract: Polygonum multiflorum is a traditional Chinese medicine with commonly clinical application. With increasing cases of Polygonum multiflorum related hepatotoxicity reported, the drug safety problem has been received more and more attention. This article reviews the toxicity characteristics of Polygonum multiflorum from the aspects of clinical cases, chemical composition and toxic material basis, and hepatotoxicity mechanism. We aim to provide a useful reference for the clinical use and mechanism research of Polygonum multiflorum.

Key words: Polygonum multiflorum, hepatotoxicity, liver injury, toxic material basis

CLC Number:

R994.2

YU Ruili, MEN Weijie, ZHOU Kun, YU Yingli. Research Progress on Toxic Material Basis and Hepatotoxicity Mechanism of Polygonum Multiflorum[J]. Chinese Journal of Pharmacovigilance, 2019, 16(8): 496-503.

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