Abstract: Objective To analyze the drug treatment of severe infection with torsade de pointes(TdP), so as to investigate the method of pharmaceutical care. Methods Clinical pharmacists were active in the whole process of 1 case of secondary severe infection with TdP, assisted physicians to develop individualized therapeutic regimen and delivered special pharmaceutical care in main drug therapy. Results Clinical pharmacists can assist clinicians to adjust the therapeutic regimen, and take effective interventions to the adverse drug reaction, improve the level of clinical drug treatment. Conclusion The clinical pharmacists take advantage of the pharmaceutical knowledge as the entry point,offer pharmaceutical care for patients timely and rationally, which ensure medication safety and efficacy．

Key words: voriconazole, hypokalemia, torsade de pointes(TdP), pharmaceutical care