Determination of Ephedrine Hydrochloride in Huanglong Zhike Granules by HPLC

Abstract

Abstract: Objective To establish a RP-HPLC method for the determination of ephedrine hydrochloride in Huanglong Zhike granules. Methods Agilent Extend C18 column was used. The mobile phase was acetonitrile-0.1% phosphoric acid(0.1% triethyamine) (10:90). The detection wavelength was set at 207nm. Results A good linearity was obtained in the range of 0.0700μg to 1.400μg(r=1.0000). The average recovery was 98.7%. Conclusion This method is simple, accurate and reproducible, and can be used for the quality control.

Key words: HPLC, Huanglong Zhike granules, ephedrine hydrochloride, determination

CLC Number:

R914.1

LIU Hong ,TIAN Hong -gen. Determination of Ephedrine Hydrochloride in Huanglong Zhike Granules by HPLC[J]. Chinese Journal of Pharmacovigilance, 2013, 10(4): 205-206.

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Determination of Ephedrine Hydrochloride in Huanglong Zhike Granules by HPLC

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