Chinese Journal of Pharmacovigilance ›› 2010, Vol. 7 ›› Issue (3): 162-163.

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Retrospectively Survey and Analysis of the Adverse Drug Reaction in 216 Patients Using Fluoroquinolones

GUO Xiao-ying, LI Qing-shan, CHENG Jing-min*   

  1. Shanxi Medical University, Shanxi Taiyuan 030001, China
  • Received:2016-02-19 Revised:2016-02-19 Online:2010-03-08 Published:2016-02-19

Abstract: Objective By analyzing 216 advense drug reaction reports received in a hospital,we explore the clinical manifestations of fluoroquinolones' adverse reactions and their distribution. Mothods In this article we retrospectively survey and analyze the adverse reactions that occur in patients using fluoroquinolones. Results We find Male patients significantly more than female patients, adverse events occurred mainly in the nervous system, allergic reactions, skin and its annexes, and local and oral incidence of adverse reactions was significantly lower than intramuscular injection and intravenous injection.Conlusion Fluoroquinolones should be rationally used. We should strictly control their in-dications, con-traindications and the quantity of separate and combined to avoid unreasonable use. We should make its mechanism clear to decrease the occurrence rate of adverse reactions and play its clinical efficacy better.

Key words: fluoroquinolones, adverse drug reaction, retrospective analysis

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