Abstract: Objective To explore the general pattern and characteristics of adverse drug reactions(ADR) induced by Shengmai injection so as to provide references for clinical rational use of drug. Methods ADR of Shengmai Injection in 59 case, reported in domestic medical journals from 1994~2008, were collected and analyzed. Results the ADR of Shengmai injection were independent of patient's age and denpendent of patient's sex, male patient were more than female patient. The onset of ADR was usually within 30min after injection. ADR could involve in multiple organs and systems, and clinical manifestations were various, mainly were allergic reaction. Severe allergic reaction could result in anaphylactic shock. Conclusion Doctors and pharmacists should know the pattern and characteristics of ADR, and the use of Shengmai injection should be under strict monitoring to reduce the occurrence of serious ADR.

Key words: Shengmai injection, adverse drug reaction(ADR), literature, analysis