Research Progress on the Potential Therapeutic Effect of Bushen Shengjing Prescription on Oligoasthenozoospermia

doi:10.19803/j.1672-8629.20240593

Abstract

Abstract: Objective To explore the potential therapeutic effects of Bushen Shengjing prescription (BSP) on oligoasthenozoospermia (OA), providing theoretical references for subsequent research. Methods The pharmacological effects of the eight Chinese medicinal herbs in BSP and their synergistic effects in the treatment of OA were analyzed through literature review. The effect of BSP on improving sperm quality was evaluated combined with existing research data. Results BSP has shown good efficacy in the treatment of OA, possibly improving sperm quality through multiple pathways such as antioxidation, anti-inflammation, and anti-apoptosis. Preliminary clinical studies have indicated that BSP can significantly increase the sperm vitality and quantity of OA patients, thereby improving fertility. Conclusion BSP has significant therapeutic potential in the treatment of OA, and its multi-component, multi-target mechanism of action provides a new treatment strategy for OA. Future research should further verify and study the efficacy and mechanism of action of BSP to promote its widespread clinical application.

Key words: Bushen Shengjing Prescription, Oligoasthenozoospermia, Research Progress, Sperm Quality, Sperm Vitality, Sperm Count, Male Infertility, Traditional Chinese Medicine

CLC Number:

R994.11

BAI Xue, CHEN Yafei, TANG Tian, LIU Zhejun, TAN Tianyang, LIU Zhenquan. Research Progress on the Potential Therapeutic Effect of Bushen Shengjing Prescription on Oligoasthenozoospermia[J]. Chinese Journal of Pharmacovigilance, 2024, 21(11): 1243-1249.

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https://zgywjj.magtechjournal.com/EN/Y2024/V21/I11/1243

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