Abstract: By introducing good pharmacovigilance prctice on management and reporting of adverse reactions to medicinal products in EU, it was more cleared to know the definition of adverse reactions and working process in EU, such ascollection of reports, validation of reports, follow-up of reports, data management, quality management.It provided the example and refrence for perfecting and developing drug adverse reaction reporting and monitoring system in China.

Key words: European Union, pharmacovigilance, adverse reactions, management, reporting