Determination of Emodin in Zhijiangning Tablet by HPLC

Chinese Journal of Pharmacovigilance ›› 2013, Vol. 10 ›› Issue (10): 614-615.

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Determination of Emodin in Zhijiangning Tablet by HPLC

GENG Hai -xia¹, WANG Hong -ming^2*

1.Bincheng Food and Drug Administration, Shandong Binzhou 256600, China;
2.Binzhou Institute for Drug Control, Shandong Binzhou 256618, China

Received:2013-07-15 Revised:2016-03-09 Online:2013-10-08 Published:2016-03-09

Abstract

Abstract: Objective To establisha RP -HPLC method for the determination of emodin in Zhijiangning tablet. Methods Agilent Extend C18 column was used. The mobile phase was methanol -0.1% phosphoric acid (80:20). The detection wavelength was set at 290nm. Results A good linearity was obtained in the range of 0.005025μg to 0.1005μg(r=0.9999).The average recovery was 99.2%. Conclusion The method is simple,accurate and repeatable and can be used for the quality control.

Key words: HPLC, Zhijiangning tablet, emodin, determination

CLC Number:

R917

GENG Hai -xia, WANG Hong -ming . Determination of Emodin in Zhijiangning Tablet by HPLC [J]. Chinese Journal of Pharmacovigilance, 2013, 10(10): 614-615.

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Determination of Emodin in Zhijiangning Tablet by HPLC

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