Chinese Journal of Pharmacovigilance ›› 2012, Vol. 9 ›› Issue (7): 431-432.

• Orginal Article • Previous Articles     Next Articles

Analysis on the Adverse Drug Reactions / Events of Paroxetine

CHENG Li-ling, XU Zuo-guo*   

  1. Psycho-rehabilitation Hospital of Yantai City, Shandong Laiyang 265200, China
  • Received:2012-02-22 Online:2012-07-10 Published:2015-08-07

Abstract: ObjectiveTo investigate the adverse drug reactions of Paroxetine, provide a reference for clinical safe use of drugs. MethodsStatistically analyzed the articles about adverse reactions of Paroxetine published by mental illness journals for the past 10 years and medical records collected by the author. ResultsThe adverse reactions of Paroxetine involve 9 major categories, with 22 kinds of clinical manifestations, mainly including extrapyramidal reactions(27.91%), blood system injury(11.63%) and allergic reactions(13.95%). ConclusionThe adverse drug reactions of Paroxetine are relatively more but gentle, focusing on extrapyramidal injury, hepatic dysfunction, leucopenia and skin allergy.

Key words: Paroxetine, adverse reaction