Chinese Journal of Pharmacovigilance ›› 2011, Vol. 8 ›› Issue (6): 323-326.

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Study on the Effect of Ethanol Extract of Xigui on Anti-fatigue

DONG Shou-tang1, WANG Cheng-jun2, LIU Jia-cheng2, DU Yi-min2   

  1. 1. Baoshan College of Traditional Chinese Medicine, Yunnan Baoshan 678000, China;
    2. Faculty of Pharmacy, Dali University, Yunnan Dali 671000, China
  • Received:2015-08-27 Revised:2015-08-27 Online:2011-06-10 Published:2015-08-27

Abstract: Objective To study the action of anti-fatigue of Xigui in mice. Methods Using the Methods of the weight loading swimming test, the acute cerebral ischemia irritable/hypoxic test, the sodium nitrite intoxation test, the low-temperature test and theautonomic activities test, which to research the function of anti-fatigue of Xigui in mice. Results Xigui could significantly prolong the time of loaded-swimming, delay the survival time of sodium nitrite poisoning and prolong the breathing time of the mice cut heads. It could increase the survival rate of low-temperature in mice, and shorten the time of spontaneous motion at 30min、60min、120min after the last administration(P<0.05 or P<0.01). Conclusion Xigui has the obvious function of anti-fatigue.

Key words: Xigui, mice, anti-fatigue

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