Research Development on the Prevention of Cerebral Ischemia in Angelica sinensis Related with Efficacy and Material Basis

Abstract

Abstract: Objective By combing pertinent literature, and summarizing the current states of the prevention of cerebral ischemia in Angelica sinensis related with efficacy and material basis, to identify its effective composition, offer the accordance and research ideas for further research on the relationship between efficacy and chemical composition of Angelica sinensis. Methods The related references in recent 10 years both at home and abroad about Angelica sinensis were analyzed, collated and summarized. Results The Angelica sinensis has many kinds of bioactive ingredients and extensive pharmacological effects. It has been used in clinical to treat the anemic cerebrovascular disease, and obtains the good curative effect. Conclusion The research of efficacy and material basis in Angelica sinensis has limits in embarks from its effective component, the mechanisms of treating the anemic cerebrovascular disease are not definite completely. The pharmaceutical chemistry ingredient is complex, and has variously uses. It needs to be further study of the effective monomer ingredient, the target and the related protection mechanism research, to expound that its curative effect and does with the mechanism provides the theory basis, with the aim of instructing the clinical reasonable medication and the new medicine research.

Key words: Angelica sinensis, efficacy, material basis, cerebral ischemia

CLC Number:

R282

SUN Rong, ZHANG Ya-nan, LV Li-li. Research Development on the Prevention of Cerebral Ischemia in Angelica sinensis Related with Efficacy and Material Basis[J]. Chinese Journal of Pharmacovigilance, 2011, 8(10): 615-618.

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