Abstract: With the development of medical standards and pharmaceutical industries, the application of hypoglycemic agents has played a significant role in the treatment of diabetes, but at the same time, drug-induced adverse reactions and rational use of drugs during the treatment of diabetes has also become to be the practical problems. In this paper, through a preliminary dissertation on the safety of sulfonylureas hypoglycemic agents, The purpose is to provide a reference of clinical rational use of drugs.

Key words: Sulfonylurea, type 2 diabetes, Security