Chinese Journal of Pharmacovigilance ›› 2010, Vol. 7 ›› Issue (12): 751-754.

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Analysis on 4750 Adverse Drug Reaction Cases of Anti-tuberculosis Drugs

FENG Hong-yun, CHEN Yi-xin   

  1. Center for Drug Reevaluation, SFDA, Beijing 100045, China
  • Received:2010-09-13 Revised:2016-03-09 Online:2010-12-08 Published:2016-03-09

Abstract: Objective To investigate the general conditions and harm to patients of anti -tuberculosis drugs, and to provide informations for rational administration. Methods The adverse drug reaction(ADR) cases of antituberculosis drugs in national ADR monitoring database were retrieved and analyzed statistically. Results There were ADR of anti-tuberculosis drugs were in every age group. The ADR of anti-tuberculosis drugs involved liver and gall system, happened in 50 days after medication, and the prognosis of anti-tuberculosis drugs ADR was well. Conclusion In order to ensure the effective anti-tuberculosis treatment, clinicians should be familiar with the common ADR of antituberculosis drugs, detect and deal with the ADR of anti-tuberculosis drugs in time, and reduce possibly the severity. consequence of the ADR of anti-tuberculosis drugs.

Key words: adverse drug reaction(ADR), anti-tuberculosis drug, national ADR monitoring database

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