Abstract: Objective In order to provide reference for clinical rational use of Shuxuening injection by analysis of 154 reports of serious drug adverse reaction induced by Shuxuening injection. Methods 154 reports of serious drug adverse reaction induced by Shuxuening injection were statistical analyzed from 2004 to 2009 in Qinghai Center for ADR monitoring. Results Serious adverse reactions were include skin damage and annex damage, systemic damage, central and peripheral nervous system damage, gastrointestinal system damage/respiratory damage and other accounted for 85.62%. Anaphylactic shock, dyspnean suffocating, laryngeal edema and other is the mainly serious adverse reactions, none of dieth and sequelae case. Conclusion We should enhance the rational use and monitoring of Shuxuening injection to avoid adverse reactions.

Key words: Shuxuening injection, adverse reaction