Process of Cutting Polygonum multiflorum Slices Based on Chemical Composition

doi:10.19803/j.1672-8629.20250369

Abstract

Abstract: Objective To investigate the differences in the distribution of main chemical components in different medicinal parts of Polygonum multiflorum decoction pieces, and to explore the applicability of processing techniques for removing the two ends of the plant. Methods A liquid chromatography-mass spectrometry system was used to find out about the differences in the content distribution of eleven chemical components in the middle and at both ends of Polygonum multiflorum decoction pieces sold in four areas of production. Results The distribution of the eleven chemical components measured in Polygonum multiflorum was higher at both ends than in the middle. Among these components, the content of 2,3,5,4 '- tetrahydroxystilbene-2-O-β-D-glucoside (trans-THSG) at either end was twice that of the middle. In addition, the contents of emodin-8-O-β-D-glucoside and quercetin-8-O-β-D-glucoside at either end of the samples from three of the areas of production were almost twice those of the middle. In Polygonum multiflorum decoction pieces of different origins, the distribution of trans-THSG, emodin-8-O-β-D-glucoside and quercetin-8-O-β-D-glucoside was considerably different. Conclusion The processing method-removing both ends of Polygonum multiflorum-can reduce the contents of trans-THSG, emodin-8-O-β-D-glucoside, and quercetin-8-O-β-D-glucoside in the decoction pieces to some extent, thereby lowering the risk of hepatotoxicity of Polygonum multiflorum.

Key words: Polygonum multiflorum, Decoction Pieces, Processing, Chemical Composition, 2,3,5,4 '- tetrahydroxystilbene-2-O-β-D-glucoside, emodin -8-O-β-D-glucoside, quercetin-8-O-β-D-glucoside, Quality

CLC Number:

R961

WANG Qi, LI Yanyi, YANG Yanrong, SHI Jia. Process of Cutting Polygonum multiflorum Slices Based on Chemical Composition[J]. Chinese Journal of Pharmacovigilance, 2025, 22(10): 1087-1093.

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https://zgywjj.magtechjournal.com/EN/Y2025/V22/I10/1087

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