Chinese Journal of Pharmacovigilance ›› 2024, Vol. 21 ›› Issue (9): 1025-1028.
DOI: 10.19803/j.1672-8629.20240286

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Quality standard for licorice of different sources

YANG Le1, SHAN Lianlian2, WANG Yali2, YAN Shunhua2, ZHOU Gang2#, CHEN Jia3,*, WEI Feng3   

  1. 1Center for Drug Reevaluation of NMPA/NMPA, Key Laboratory for Research and Evaluation of Pharmacovigilance, Beijing 100076, China;
    2Xinjiang Uygur Autonomous Region Institute for Drug Control, Urumqi Xinjiang 830054, China;
    3National Institutes for Food and Drug Control, Beijing 102629, China
  • Received:2024-03-12 Online:2024-09-15 Published:2024-09-14

Abstract: Objective To analyze the problems with the quality of Glycyrrhiza inflata Bat. and Glycyrrhiza glabra L., identify obstacles to development and offer solutions. Methods Through talks with enterprises, field investigation, literature research and studies on the quality standard for Glycyrrhiza inflata Bat. and Glycyrrhiza glabra L., the status quo of the Glycyrrhiza inflata Bat. and Glycyrrhiza glabra L. industry in Xinjiang, the problems with pharmaceutical standards and opportunities of development were analyzed. Results The rate of defective Glycyrrhiza inflata Bat. and Glycyrrhiza glabra L. in the medicinal field was high by the content determination standard specified in the Pharmacopoeia of the People's Republic of China (2020 edition). However, the licorice of three sources contained flavonoids with pharmacological action, so liquiritin alone could not be used as an indicator of quality control. Conclusion It is recommended that the quality standard for Glycyrrhiza inflata Bat. and Glycyrrhiza glabra L. be revised to adopt various flavonoid components as the quality evaluation indexes of licorice so as to promote its cultivation in China.

Key words: licorice, Glycyrrhiza inflata Bat., Glycyrrhiza glabra L., liquiritin, quality, standard, origin

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