Advances in Research on Impact of Drug Excipients on Safety of Diagnosis and Treatment

doi:10.19803/j.1672-8629.2021.05.19

Abstract

Abstract: Objective To find out more about the influence of drug excipients in preparations on the safety of diagnosis and treatment and to provide reference for safe and rational use of drugs. Methods Recent literature related to the physiological activity, physical and chemical properties of drug excipients that affected the diagnosis and treatment process was reviewed. Results The inherent properties of drug excipients often acted on the human body clinically in conjunction with other factors of health care, which could adversely impact the outcome of a disease and the judgment of health care providers. Adverse drug reactions (ADR) caused by drug excipients were often related to their inherent properties. Conclusion As essential ingredients of preparations, drug excipients could make difference to the safety of clinical medication in the process of diagnosis and treatment. Drug excipients deserve the same amount of attention as the main active ingredients of preparations in order to minimize medication risks.

Key words: drug excipients, properties of drug excipients, adverse drug reactions (ADR), safe medication, drug interactions

CLC Number:

R944

ZHANG Tai, WANG Yanyan. Advances in Research on Impact of Drug Excipients on Safety of Diagnosis and Treatment[J]. Chinese Journal of Pharmacovigilance, 2021, 18(5): 492-494.

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