Research Progress on Pharmacological Effects and Toxicity of Gardenia jasminoides Ellis and Related Mechanisms

doi:10.19803/j.1672-8629.2021.01.20

Abstract

Abstract: Gardenia jasminoides Ellis (G.jasminoides)is a commonly used traditional Chinese medicine and also a healthy food in China.It is mainly used for the treatment of acute/chronic viral hepatitis,hyperbilirubinemia,children's fever,hyperlipidemia and diabetes,with significant pharmacological effects.However,in recent years,more reports and studies have suggested that G.jasminoides has apparent toxicity and results in adverse effects,which restricts clinical administration of G.jasminoides.Therefore,in order to improve the rational use of G.jasminoides in clinic,enhance the efficacy of G.jasminoides and prevent or reduce the toxicity caused by gardenia,this review summarized the pharmacological effects and toxicity of G.jasminoides and the relatedt mechanisms.

Key words: Gardenia jasminoides Ellis, pharmacodynamic effect, hepatotoxicity, nephrotoxicity

CLC Number:

R285

WANG Xiaohui, ZHANG Fan, XI Lili, XIA Wenbin, WEI Yuhui. Research Progress on Pharmacological Effects and Toxicity of Gardenia jasminoides Ellis and Related Mechanisms[J]. Chinese Journal of Pharmacovigilance, 2021, 18(1): 94-99.

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