缩宫素注射液致严重过敏样反应1例分析

doi:10.19803/j.1672-8629.20240316

中国药物警戒 ›› 2024, Vol. 21 ›› Issue (10): 1169-1171.
DOI: 10.19803/j.1672-8629.20240316

缩宫素注射液致严重过敏样反应1例分析

巨康璐, 常瑛, 刘振国^*

西北妇女儿童医院药剂科,陕西西安 710061

收稿日期:2023-05-10 出版日期:2024-10-15 发布日期:2024-10-14
通讯作者: ^*刘振国,男,博士,副主任药师,临床药学与分子药理学。E-mail:liu.zhenguo@outlook.com
作者简介:巨康璐,女,硕士,药师,妇产科临床药学。
基金资助:
陕西省重点研发计划（2024SF-YBXM-159）

One case of severe allergic reactions caused by oxytocin injection

JU Kanglu, CHANG Ying, LIU Zhenguo^*

Department of Pharmacy, Northwest Women's and Children's Hospital, Xi'an Shaanxi 710061, China

Received:2023-05-10 Online:2024-10-15 Published:2024-10-14

摘要/Abstract

摘要： 目的分析缩宫素注射液致严重过敏样反应的病例,为临床安全合理用药提供参考。方法分析1例稽留流产患者,在清宫术后使用缩宫素注射液连续用药第2天,在静脉滴注2 min后发生严重过敏样反应的病例,并进行文献回顾性分析,探讨其原因及防治措施。结果患者发生的严重过敏样反应很可能与缩宫素注射液有关,此类情况在临床比较少见。患者经有效的抗过敏治疗后,症状好转。结论临床应用缩宫素注射液时,需全程防范严重过敏样反应的发生,及早发现与处理。

关键词: 缩宫素, 注射液, 严重过敏样反应, 药品不良反应

Abstract: Objective To analyze severe allergic reactions caused by oxytocin injection so as to provide references for safe and rational drug use. Methods One rare case of severe allergic reactions in a patient with missed abortion was reported, who had manifested critical symptoms after two minutes of intravenous infusion of oxytocin on the second day of continuous injection. Related literature was retrospectively analyzed. The causes and preventive measures were studied. Results The severe allergic reactions were likely related to oxytocin injection, and such cases were very rare. The symptoms were relieved after effective anti-allergic treatment. Conclusion Clinicians need to prevent severe allergic reactions caused by oxytocin injection, and early detection and treatment are crucial.

Key words: oxytocin, injection, severe anaphylactic reaction, adverse drug reaction

中图分类号:

巨康璐, 常瑛, 刘振国. 缩宫素注射液致严重过敏样反应1例分析[J]. 中国药物警戒, 2024, 21(10): 1169-1171.

JU Kanglu, CHANG Ying, LIU Zhenguo. One case of severe allergic reactions caused by oxytocin injection[J]. Chinese Journal of Pharmacovigilance, 2024, 21(10): 1169-1171.

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缩宫素注射液致严重过敏样反应1例分析

One case of severe allergic reactions caused by oxytocin injection

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