己酮可可碱注射液致慢性肾功能衰竭患者过敏性休克1例分析

doi:10.19803/j.1672-8629.20240611

摘要/Abstract

摘要： 目的研究己酮可可碱注射液致过敏性休克病例,为临床合理用药提供参考。方法分析1例慢性肾衰竭成人患者使用己酮可可碱导致过敏性休克的案例,通过文献回顾己酮可可碱导致过敏性休克的情况,讨论原因及防治措施。结果根据患者的临床表现及药物与用药时间的关联性,考虑己酮可可碱导致过敏性休克,患者经有效抗过敏治疗后,过敏性休克症状得到缓解。结论己酮可可碱注射液可能会导致慢性肾功能衰竭患者发生过敏性休克,用药期间应加强不良反应监测,促进临床安全合理用药。

关键词: 己酮可可碱, 注射液, 过敏性休克, 慢性肾衰竭, 药品不良反应

Abstract: Objective To analyze the characteristics of anaphylactic shock caused by pentoxifylline injection and provide a reference for rational drug use in clinic. Methods One case of anaphylactic shock caused by pentoxifylline in an adult with chronic kidney disease was reported. Related literature was reviewed to find out more about pentoxifylline-caused anaphylactic shock before the causes and prevention measures were analyzed. Results Based on the patient’s manifestations and the correlations between medication and time of administration, pentoxifylline was considered to have caused anaphylactic shock. After effective anti-allergic treatment, the patient’s symptoms of anaphylactic shock were relieved. Conclusion Pentoxifylline injection may increase the risk of anaphylactic shock in patients with chronic kidney disease. Adverse reactions should be monitored during medication to promote safe and rational drug use in clinical practice.

Key words: Pentoxifylline, Injections, Anaphylactic Shock, Chronic Renal Failure, Adverse Drug Reaction

中图分类号:

R977
R994.11

陈芬, 王素萍. 己酮可可碱注射液致慢性肾功能衰竭患者过敏性休克1例分析[J]. 中国药物警戒, 2025, 22(4): 469-471.

CHEN Fen, WANG Suping. One Case of Allergic Shock Caused by Pentoxifylline Injection in a Patient with Chronic Renal Failure[J]. Chinese Journal of Pharmacovigilance, 2025, 22(4): 469-471.

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