超说明书使用注射用尖吻蝮蛇血凝酶致小腿肌间静脉血栓形成1例

中国药物警戒 ›› 2018, Vol. 15 ›› Issue (9): 572-573.

超说明书使用注射用尖吻蝮蛇血凝酶致小腿肌间静脉血栓形成1例

江永贤, 李根^*, 王涵, 李莉

成都市妇女儿童中心医院,四川成都 610000

收稿日期:2018-11-02 修回日期:2018-11-02 出版日期:2018-09-20 发布日期:2018-11-02
通讯作者: 李根,男,学士,主任药师,医院药学。E-mail：627045226@qq.com
作者简介:江永贤,女,硕士,主管药师,质控药学。

One Case of Muscular Calf Vein Thrombosis Induced by Off -label Use of Haemocoagulase Agkistrodon for Injection

JIANG Yongxian, LI Gen^*, WANG Han, LI Li

Chengdu Women's & Children's Central Hospital, Sichuan Chengdu 610000, China

Received:2018-11-02 Revised:2018-11-02 Online:2018-09-20 Published:2018-11-02

摘要/Abstract

中图分类号:

R965

江永贤, 李根, 王涵, 李莉. 超说明书使用注射用尖吻蝮蛇血凝酶致小腿肌间静脉血栓形成1例[J]. 中国药物警戒, 2018, 15(9): 572-573.

JIANG Yongxian, LI Gen, WANG Han, LI Li. One Case of Muscular Calf Vein Thrombosis Induced by Off -label Use of Haemocoagulase Agkistrodon for Injection[J]. Chinese Journal of Pharmacovigilance, 2018, 15(9): 572-573.

参考文献

[1] 刘建平,邢建民.循证的药品不良反应评价方法[J].中国药物警戒,2010,17(1):12-15.
[2] 范燕,汤韧,井春梅,等.药学期刊药品不良反应案例报道论文的要点探讨[J].中国药物警戒,2017,1(2):101-103.
[3] 张鹏,李静,左燕.大剂量静注蛇毒血凝酶注射液致深静脉血栓1例[J].西北药学杂志,2014,29(2):185-186.
[4] 袁秋雄. 巴曲亭致急性多发性大面积脑梗死[J].现代医药卫生,2008,24(24):3782-3783.
[5] Solomon E R, Frick A C, Paraiso M F, et al.Risk of deep venous thrombosis and pulmonary embolism in urogynecologic surgical patients[J].Am J Obstet Gynecol,2010,203(5):510-511.
[6] Kumar S, Al-Wahab Z, Sarangi S, et al.Risk of postoperative venous thromboembolism after minimally invasive surgery for endometrial and cervical cancer is low: a multi-institutional study[J].Gynecol Oncol,2013,130(1):207-212.
[7] Qu H, Li Z, Zhai Z, et al.Predicting of venous thromboembolism for patients undergoing gynecological surgery[J]. Medicine (Baltimore), 2015,94(39):e1653.
[8] 魏戌,谢雁鸣. 国内外不良反应因果判断原则及评价方法解读[J].中国中药杂志,2012,37(18):2744-2747.
[9] 张宁,李心蕾,袁偲偲,等.注射用尖吻蝮蛇血凝酶不良反应报告分析及文献汇总[J].临床药物治疗杂志,2017,15(7):40-43.
[10] Cheng S, Wang C, Li J, et al.Determination of Hemocoagulase Agkistrodon in a Pharmaceutical Preparation by High-Performance Liquid Chromatography with Pre-Column Derivatization and Fluorescence Detection[J]. Journal of Chromatographic Science, 2013, 51(6):552-559.
[11] 石光,庞建新,曹莹,等.尖吻蝮蛇血凝酶药效评价及其作用机制[J].中国新药杂志,2010,19(18):1706-1709.
[12] 于明帅,张科.尖吻蝮蛇血凝酶临床止血作用及安全性研究进展[J].四川医学,2015,39(1):106-108.
[13] 凌端强,杨涛,郝斌. 小腿肌间静脉丛血栓形成认识及诊治进展[J].血管与腔内血管外科杂志,2015,1(2/3):185-189.
[14] Schwarz T, Schmidt B, Beyer J, et al.Therapy of isolated calfmuscle vein thrombosis with low-molecular-weight heparin[J].Blood Coagulation & Fibrinolysis:an International Journalin Haemostasis and Thrombosis,2001,12(7):597-599.
[15] 刘玉珍,张震宇,郭淑丽,等.妇科盆腔手术后下肢深静脉血栓形成的临床研究[J].中华妇产科杂志,2006,41(2):107-110.
[16] 郎景和,王辰,瞿红,等.妇科手术后深静脉血栓形成及肺栓塞预防专家共识[J].中华妇产科杂志,2017,52(10):649-653.
[17] 张迎辉. 尖吻蝮蛇血凝酶在妇科手术中应用的安全性及有效性观察[J].中国临床药理学杂志,2011,4(27):259-261.