中国药物警戒 ›› 2017, Vol. 14 ›› Issue (10): 635-637.

• 安全性评价与合理用药 • 上一篇    下一篇

老年缺血性脑卒中患者院外二级预防用药的依从性情况及影响因素分析

冯华军   

  1. 常州市金坛区人民医院病区药房，江苏常州213200
  • 收稿日期:2017-08-08 修回日期:2017-11-30 出版日期:2017-10-20 发布日期:2017-11-30
  • 作者简介:冯华军，男，本科，主管药师，临床药学。

Study on Medication Compliance and It's Influence Factors of Extramural Hospital Second Grade Prevention for Senile Ischemic Stroke

FENG Hua-jun   

  1. Ward Pharmacy of Jintan District People's Hospital in Changzhou City, Jiangsu Changzhou 213200, China
  • Received:2017-08-08 Revised:2017-11-30 Online:2017-10-20 Published:2017-11-30

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摘要： 目的 研究老年缺血性脑卒中患者的院外二级预防用药依从性情况及依从性的影响因素。方法 选取60岁以上的老年缺血性脑卒中复发患者，收集其基本信息及住院治疗前既往用药情况，分析不同因素对患者院外二级预防用药依从性的影响，进而分析预防用药依从性对缺血性脑卒中疗效的影响。结果 本研究纳入的257例老年缺血性脑卒中患者，年龄60~75岁、饮食清淡、家庭收入稳定、与子女同住、发作次数在4次及以上患者依从性较好，且具有统计学意义（P <0.05）。与无合并症患者相比，伴随高血压、高血脂、糖尿病及血栓性疾病的患者的依从性显著提高，差异具有统计学意义（P <0.05）。Logistic回归模型结果显示，饮食习惯、年龄、家庭因素、运动习惯、发病次数、伴随高血压及伴随高血脂均是影响脑卒中患者二级预防用药依从性的因素，差异具有统计学意义（P <0.05）。结论 老年缺血性脑卒中患者的院外二级预防用药依从性高低与患者自身生活饮食习惯、年龄、家庭因素、运动习惯、发病次数、高血压、高血脂相关，对于首次发病的老年伴随高血压、血脂异常的患者应更加提高重视。

关键词: 老年缺血性脑卒中, 二级预防用药, 依从性影响因素

Abstract: Objective To study the medication compliance and it's influence factors of second grade prevention for senile ischemic stroke patients. Methods Over 60 years old patients with ischemic stroke were selected. The data including basic information and medication history of them was collected. Then, the influence of medication compliance on the treatment effect was explored. Results 257 cases patients with ischemic stroke were collected as subjects for study. The factors such as 60~75 years old, light diet, stable household income, live with their children, attack numbers more than 4 times were benefit to medication compliance (P<0.05). The results of logistic regression showed, life diet habit, age, family factors, exercise habits, onset frequency, hypertension and hyperlipidemia were influence factors of medication compliance (P <0.05). Conclusion For senile ischemic stroke patients, the medication compliance was relate with life diet habit, age, family factors, exercise habits, onset frequency, hypertension and hyperlipidemia. We should pay more attention on patients with first onset of hypertension or dyslipidemia.

Key words: senile ischemic stroke, second grade prevention medication, compliance influence factor

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