药用真菌种质资源保护利用现状与思考

doi:10.19803/j.1672-8629.20240144

中国药物警戒 ›› 2024, Vol. 21 ›› Issue (5): 481-488.
DOI: 10.19803/j.1672-8629.20240144

药用真菌种质资源保护利用现状与思考

刘天睿^1,2,3, 高海云^1,2, 陈瑜鑫^1,2, 李瑶^1,2, 李慧^1,2, 袁媛^1,2,4,5,*

¹中国中医科学院中医药健康产业研究所,中药资源可持续利用江西省重点实验室,江西南昌 330115;
²江西中医药健康产业研究院,江西南昌 330115;
³昭通学院,云南省天麻与真菌共生生物学重点实验室,云南昭通 657099;
⁴中国中医科学院中药资源中心,道地药材品质保障与资源持续利用全国重点实验室,北京 100700;
⁵青海民族大学化学化工学院,青海西宁 810007

收稿日期:2024-02-29 出版日期:2024-05-15 发布日期:2024-05-13
通讯作者: ^*袁媛,女,博士,研究员·博导,中药鉴定与分子生药学。E-mail：y_yuan0732@163.com
作者简介:刘天睿,男,博士,助理研究员,药用真菌资源开发利用。
基金资助:
中央级公益性科研院所基本科研业务费专项（ZZ16-ND-12、ZZ16-XRZ-105）; 中国中医科学院科技创新工程重大攻关项目（CI2021B014、CI2023D001/CI2023E002-04）; 中央本级重大增减支项目（2060302）; 江西省“双千计划”项目（TMKF2023B01）; 国家杰出青年科学基金（82325049）; 云南省天麻与真菌共生生物学重点实验室开放课题项目（TMKF2023B01）; 青海省“昆仑英才·高端创新创业人才”计划项目

Current situation of conservation and utilization of medicinal fungal germplasm resources and reflection

LIU Tianrui^1,2,3, GAO Haiyun^1,2, CHEN Yuxin^1,2, LI Yao^1,2, LI Hui^1,2, YUAN Yuan^1,2,4,5,*

¹Key Laboratory of Sustainable Utilization of Traditional Chinese Medicine Resources in Jiangxi Province, Institute of Traditional Chinese Medicine Health Industry, China Academy of Chinese Medical Sciences, Nanchang Jiangxi 330115, China;
²Jiangxi Health Industry Institute of Traditional Chinese Medicine, Nanchang Jiangxi 330115, China;
³Yunnan Key Laboratory of Gastrodia and Fungi Symbiotic Biology, Zhaotong University, Zhaotong Yunnan 657099, China;
⁴State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica China Academy of Chinese Medical Sciences, Beijing 100700, China;
⁵School of Chemistry and Chemical Engineering, Qinghai Minzu University, Xining Qinghai 810007, China

Received:2024-02-29 Online:2024-05-15 Published:2024-05-13

摘要/Abstract

摘要： 目的综述我国药用真菌种质资源保护利用现状,推动药用真菌高质量发展。方法对我国药用真菌资源分布、种质资源库建设及种质资源保存、种质创新利用等方面进行论述,依据发展现状和远景定位,指出现阶段我国药用真菌资源发展存在的问题,并提出针对性发展建议。结果我国药用真菌资源丰富,分布广泛,但尚有95.1%的真菌种类有待发现、研究和开发利用;药用真菌种质资源的收集与保藏尚不全面,未形成规模化、系统化的保藏中心和管理平台,制约了菌物药产业的发展;药用真菌良种和新品种选育进程较缓慢。结论药用真菌资源作为我国独特的优势资源,其资源开发与利用仍有很长的路要探索。加大药用真菌种质资源的收集与保护力度、开展物质基础研究和功效评价研究、建立国家药用真菌产业技术体系、加快药用真菌良种和新品种选育等一系列工作迫在眉睫。

关键词: 药用真菌, 种质资源, 菌种保藏, 开发利用, 菌物药, 新品种选育

Abstract: Objective To review the conservation and utilization of medicinal fungal germplasm resources in China, and promote the high-quality development of medicinal fungi. Methods Discuss the distribution of medicinal fungi resources, construction of germplasm resource banks, preservation of germplasm resources, and innovative utilization of germplasm resources in China. Based on the current development status and long-term positioning, it points out the problems in the development of medicinal fungal resources in China at the current stage and proposes targeted development suggestions. Results China has abundant medicinal fungal resources and a wide distribution, but 95.1% of fungal species remained to be discovered, researched, developed and utilized. The collection and preservation of medicinal fungal germplasm resources are not yet comprehensive, and large-scale and systematic preservation centers and management platforms have not been formed, which restricts the development of the mycomedicine industry; The breeding process of improved and new varieties of medicinal fungi is relatively slow. Conclusion Medicinal fungal resources are a unique advantage in China, but there is still a long way to explore the development and utilization of medicinal fungal resources. It is urgent to increase the collection and protection of germplasm resources of edible and medicinal fungi, conduct research on material basis and efficacy evaluation, establish a national technical system for the medicinal fungi industry, and accelerate the selection and breeding of excellent and new varieties of medicinal fungi.

Key words: medicinal fungi, germplasm resources, strain preservation, development and utilization, mycomedicine, breeding of new varieties

中图分类号:

R969.3

刘天睿, 高海云, 陈瑜鑫, 李瑶, 李慧, 袁媛. 药用真菌种质资源保护利用现状与思考[J]. 中国药物警戒, 2024, 21(5): 481-488.

LIU Tianrui, GAO Haiyun, CHEN Yuxin, LI Yao, LI Hui, YUAN Yuan. Current situation of conservation and utilization of medicinal fungal germplasm resources and reflection[J]. Chinese Journal of Pharmacovigilance, 2024, 21(5): 481-488.

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药用真菌种质资源保护利用现状与思考

Current situation of conservation and utilization of medicinal fungal germplasm resources and reflection

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