One Case of Acute Liver Failure Caused by Amiodarone Injection

doi:10.19803/j.1672-8629.20250359

Abstract

Abstract: Objective To investigate the causes and clinical characteristics of acute liver failure induced by amiodarone in order to provide a reference for safe clinical medications. Methods One case of acute liver failure following administration of amiodarone hydrochloride injection was analyzed while the association, causes, and clinical features regarding acute liver failure caused by this drug were explored based on related literature. Results Correlation analysis showed that acute liver failure was strongly associated with amiodarone in this patient. Liver enzyme levels improved after discontinuing the medication and initiating therapy, but treatment was ultimately discontinued due to worsening condition. Conclusion Despite the low incidence of acute liver failure induced by amiodarone, the consequent adverse reactions can be severe. Clinicians should be alert to adverse drug reactions, adhere to rational and standardized prescriptions, and ensure early identification and interventions to improve the prognosis of patients.

Key words: Amiodarone, Drug-induced Liver Injury, Liver Failure, Pharmaceutical Care, Adverse Drug Reactions

CLC Number:

R972

JIANG Wenhao, XU Hongbing, ZHANG Xiaogang, WU Jiangping. One Case of Acute Liver Failure Caused by Amiodarone Injection[J]. Chinese Journal of Pharmacovigilance, 2026, 23(2): 197-199.

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https://zgywjj.magtechjournal.com/EN/Y2026/V23/I2/197

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