One Case of Severe Anaphylactic Shock Caused by Hemocoagulase Agkistrodon for Injection

doi:10.19803/j.1672-8629.20240860

Abstract

Abstract: Objective To investigate the characteristics of severe anaphylactic shock caused by hemocoagulase agkistrodon for injection in a patient with perioperative bleeding so as to provide a reference for safe clinical medication. Methods One case of severe anaphylactic shock that occurred after the use of hemocoagulase agkisttodon for injection for hemostasis in a breast cancer patient postoperatively was analyzed. Related literature was reviewed. Results The patient experienced severe anaphylactic shock immediately after using the hemocoagulase agkisttodon for injection. There was a significant temporal correlation. After quick symptomatic treatment, the patients recovered. Literature suggested that anaphylactic shock usually occurred within 30 minutes of using hemocoagulase agkistrodon. Patients with or without a history of allergies were at risk of anaphylactic shock. Conclusion The risk of anaphylactic shock caused by hemagglutinin is unpredictable, which deserves attention. Assessment of safety and precautions against adverse reactions should precede the use of this drug in high-risk populations.

Key words: Haemocoagulase Agkistrodon, Injection, Breast Cancer, Postoperative, Perioperative Bleeding, Anaphylactic Shock, Adverse Drug Reactions

CLC Number:

R973
R994.11

QIAN Fengdan, ZHANG Lichao, GONG Yifei. One Case of Severe Anaphylactic Shock Caused by Hemocoagulase Agkistrodon for Injection[J]. Chinese Journal of Pharmacovigilance, 2025, 22(9): 1051-1053.

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https://zgywjj.magtechjournal.com/EN/Y2025/V22/I9/1051

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