Research Progress in Applications of Strychnine Semen in Orthopedics and Traumatology

doi:10.19803/j.1672-8629.20240431

Abstract

Abstract: Objective To investigate the safety and rational use of Strychnos Semen in orthopedic treatments in order to ensure therapeutic efficacy while reducing the risk of toxicity. Methods The applications of Strychnos Semen in treating such conditions as fracture healing, osteoarthritis, bone hyperplasia, spinal cord injuries, cervical spondylosis, and lumbar disc herniation were analyzed. The dosage control, medication monitoring, detoxification through processing, and contraindications with other medications were studied. Results Clinical applications demonstrated that Strychnos Semen had shown significant efficacy in treating fracture healing, osteoarthritis, bone hyperplasia, spinal cord injuries, cervical spondylosis, and lumbar disc herniation. However, the presence of toxic components in Strychnos Semen had cast doubt on its safe clinical application. Conclusion Strychnos Semen contains toxic components, so more research on its safe clinical applications is required. The safe and effective use of Strychnos Semen can be facilitated by appropriately controlling dosages, monitoring medication, processing for detoxification, and avoiding improper medication combinations.

Key words: Strychnos Semen, Strychnine, Orthopedics and Traumatology, Clinical Application, Security, Rational Use of Drugs

CLC Number:

R961

YU Wenlu, ZHANG Hong. Research Progress in Applications of Strychnine Semen in Orthopedics and Traumatology[J]. Chinese Journal of Pharmacovigilance, 2025, 22(1): 116-120.

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URL: https://zgywjj.magtechjournal.com/EN/10.19803/j.1672-8629.20240431

https://zgywjj.magtechjournal.com/EN/Y2025/V22/I1/116

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