Analysis of Clinical Medications in Children with Acute Bronchopneumonia

Abstract

Abstract: ObjectiveBy collecting the medications of acute bronchopneumonia in children in our hospital, to analyze drug use in these patients, and provide some reference for the rational use of drugs. Methods The medical records of acute bronchopneumonia in children from November 2016 to November 2017 were collected, and the rationalities of the use of drugs with acute bronchopneumonia in children were analyzed. Results A total of 432 cases were collected, where 3 961 medications in total and 9.17 medications per patient were prescribed. These medications were involved in 6 types of 25 kinds of drugs, and the selection of drug varieties was generally reasonable. There were 618 irrational medical orders, accounting for 15.60% of the total medication orders. Irrationally used drugs included traditional Chinese medicine injections and antibacterial drugs. The categories of irrational use were mainly inappropriate usage/dosage and inappropriate route of administration. Conclusion The use of drugs in children with acute bronchial pneumonia in our hospital was basically reasonable, but there were still a few irrational prescriptions. The use of antibacterial drugs and traditional Chinese medicine injections should be strengthened to improve the rational use.

Key words: children, acute bronchopneumonia, antibacterial drugs, rational use of drugs

CLC Number:

R965

FANG Sixiao, YANG Yue. Analysis of Clinical Medications in Children with Acute Bronchopneumonia[J]. Chinese Journal of Pharmacovigilance, 2018, 15(12): 746-750.

References

[1] 李昌崇, 林立. 儿童下呼吸道感染常见细菌病原分布及耐药现状[J]. 临床儿科杂志, 2010 (2): 106-111.
[2] 袁壮. 50 年来小儿肺炎诊治策略的变迁[J]. 中国实用儿科杂志, 2006, 21(12): 881-908.
[3] 梁爽. 抗菌药物合理应用存在的问题及对策[J]. 临床合理用药杂志, 2016, 9(2):73-74.
[4] 赵瑛, 黄璞, 张玉,等. 喜炎平注射液儿科住院患者临床应用分析[J]. 中国医院药学杂志, 2016, 36(16):1388-1391.
[5] 马冠群, 邝俊健. 109例喜炎平注射液不良反应文献分析[J]. 中国药物警戒, 2010, 7(9):558-560.
[6] 马瑞芳, 何凡. 儿童抗病毒中药注射剂应用情况分析[J]. 国际病毒学杂志, 2016, 23(4):227-228.
[7] 中华医学会儿科学分会呼吸学组. 儿童社区获得性肺炎管理指南(2013修订)(下)[J]. 中华儿科杂志, 2013, 51(11):856-862.
[8] 肖永红, 王进, 朱燕,等. Mohnarin 2008年度全国细菌耐药监测[J]. 中华医院感染学杂志, 2010, 20(16):2377-2383.
[9] 乔建, 王亚群, 陈永志. 843 例住院患者抗菌药物应用情况调查及不合理用药分析[J]. 中国药房, 2007, 18(17): 1311-1312.
[10] 李佳凤, 王世彪, 刘光华, 等. β-内酰胺类与大环内酯类抗菌药物联合治疗重症社区获得性肺炎疗效回顾[J]. 临床儿科杂志, 2014, 32(5): 453-455.
[11] 卢金花, 张健波, 赵果邡,等. 儿科住院患儿抗菌药物使用现状调查及分析[J]. 临床合理用药杂志, 2016, 9(11):75-76.
[12] 洪建国, 陈强, 陈志敏,等. 儿童常见呼吸道疾病雾化吸入治疗专家共识[J]. 中国实用儿科杂志, 2012, 27(4):265-269.
[13] 宁俊凯, 庞素秋. 我院住院患者氧气雾化吸入给药的利用分析[J]. 中国药物警戒, 2018,15(5):304-307.
[14] 杨义琼, 李晓阳, 马利维. 复方异丙托溴铵溶液联合布地奈德雾化吸入治疗婴幼儿喘息性疾病的疗效[J]. 儿科药学杂志, 2011, 17(3):34-36.
[15] 李平, 秦中, 孙小琴,等. 布地奈德、异丙托溴铵及沙丁胺醇三联联合雾化吸入治疗小儿支原体肺炎的临床探讨[J]. 中国初级卫生保健, 2013, 27(11):115-116.